KPV + BPC-157 for gut and inflammation
KPV calms the inflammatory signaling. BPC-157 rebuilds the gut lining and tissue. Together they give two complementary levers, calm and repair.
4–8 weeks + 2–4-week washout
Why this protocol
KPV is a tripeptide that quiets inflammation from inside the cell. It lowers NF-κB, the master inflammatory switch, and reduces pro-inflammatory cytokines, with its strongest evidence in gut models. BPC-157 is studied for healing the gut lining and bringing new blood supply (angiogenesis) to repairing tissue.
Run together, KPV calms the fire while BPC-157 rebuilds the structure, so the tissue heals in a less-inflamed environment. Because they pull different levers (suppress inflammation vs. drive repair), the combination is additive, not redundant. Pairing KPV with another anti-inflammatory would just push the same lever twice.
The regimen
KPV
Calm inflammation- Dose
- 300–500 mcg
- Schedule
- Once daily · subcutaneous
- Timing
- Morning
Reconstitution calculator
Reconstitution calculator
Calculated for a 1 mL U-100 insulin syringe (100 units/mL).
Units per dose
10 units
Draw this many units on a U-100 syringe
Each unit holds 50 mcg
- Volume per dose
- 0.1 mL
- Doses per vial
- 20
- Concentration
- 5 mg/mL
One vial lasts
- Daily
- 20 days
- Every other day
- 40 days
- 5×/week
- 28 days
Research use only. Not for human consumption. Outputs are reference values based on research literature. Verify all measurements independently.
BPC-157
Repair- Dose
- 250–500 mcg
- Schedule
- Once daily · subcutaneous (co-injected)
- Timing
- Morning
Reconstitution calculator
Reconstitution calculator
Calculated for a 1 mL U-100 insulin syringe (100 units/mL).
Units per dose
5 units
Draw this many units on a U-100 syringe
Each unit holds 50 mcg
- Volume per dose
- 0.05 mL
- Doses per vial
- 40
- Concentration
- 5 mg/mL
One vial lasts
- Daily
- 40 days
- Every other day
- 80 days
- 5×/week
- 56 days
Research use only. Not for human consumption. Outputs are reference values based on research literature. Verify all measurements independently.
Cycle & schedule
- Cycle (4–8 weeks)Co-inject KPV 300–500 mcg + BPC-157 250–500 mcg once daily, drawn together or as two nearby sites, rotated across the week.
- Washout (2–4 weeks)Stop both and re-check inflammatory markers (e.g. hs-CRP) during the break to see whether the baseline has settled before repeating.
Studies behind this protocol
Research use only · Not medical advice · Updated 2026-09-24