BPC-157 + TB-500 for soft-tissue recovery
This recovery stack pairs TB-500, which draws repair cells toward the injury, with BPC-157, which rebuilds the tissue and its blood supply.
8 weeks + 4-week washout
Why this protocol
These two peptides are the most common recovery pairing because they act at different stages of repair. TB-500 (a synthetic of the Thymosin β4 protein) promotes the migration of repair cells into damaged tissue and helps new blood vessels form. BPC-157 is studied for healing connective tissue (tendon, ligament, gut lining) and for bringing fresh blood supply (angiogenesis) to the repair.
One rat study has tested the pair on a repaired Achilles tendon over 4 weeks. Only TB-500 made the tendon stronger, and the pair did no better than either peptide alone.
The regimen
BPC-157
Repair- Dose
- 250–500 mcg
- Schedule
- Once daily · subcutaneous
- Timing
- Morning; near the injury site for localized work
Reconstitution calculator
Reconstitution calculator
Calculated for a 1 mL U-100 insulin syringe (100 units/mL).
Units per dose
5 units
Draw this many units on a U-100 syringe
Each unit holds 50 mcg
- Volume per dose
- 0.05 mL
- Doses per vial
- 40
- Concentration
- 5 mg/mL
One vial lasts
- Daily
- 40 days
- Every other day
- 80 days
- 5×/week
- 56 days
Research use only. Not for human consumption. Outputs are reference values based on research literature. Verify all measurements independently.
TB-500
Cell migration- Dose
- 2–2.5 mg
- Schedule
- Twice weekly (loading) → once weekly (maintenance) · subcutaneous
- Timing
- Any time of day
Reconstitution calculator
Reconstitution calculator
Calculated for a 1 mL U-100 insulin syringe (100 units/mL).
Units per dose
40 units
Draw this many units on a U-100 syringe
Each unit holds 50 mcg
- Volume per dose
- 0.4 mL
- Doses per vial
- 5
- Concentration
- 5 mg/mL
One vial lasts
- Daily
- 5 days
- Every other day
- 10 days
- 5×/week
- 7 days
- Large draw (40 units). That's normal for mg doses. To check it, multiply the units by what each unit holds. You should get your dose.
Research use only. Not for human consumption. Outputs are reference values based on research literature. Verify all measurements independently.
Cycle & schedule
- Loading (weeks 1–6)BPC-157 250–500 mcg once daily, plus TB-500 2–2.5 mg twice weekly (≈ 4–5 mg/week). TB-500 is front-loaded in these weeks while BPC-157 runs every day.
- Maintenance (weeks 7–8)Continue BPC-157 daily; drop TB-500 to 2–2.5 mg once weekly as the repair consolidates.
- Washout (4 weeks)Stop both for about 4 weeks and reassess recovery (pain, range of motion, or imaging) before deciding whether to repeat.
Studies behind this protocol
- PMID 42542926Biçer et al., Jt Dis Relat Surg 2026 (BPC-157, TB-500 and the pair, rat Achilles tendon repair, 4 weeks)
Research use only · Not medical advice · Updated 2026-09-24