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ProtocolsRecoveryIntermediate8 weeks + 4-week washout

BPC-157 + TB-500 — Soft-Tissue Recovery

The flagship recovery stack: tb-500 mobilizes repair cells toward the injury while bpc-157 rebuilds the tissue and its blood supply — two complementary levers on one injury, not the same one twice.

Why this protocol

These two peptides are the most common recovery pairing because they act at different stages of repair. tb-500 (a synthetic of the Thymosin β4 protein) promotes the migration of repair cells into damaged tissue and helps new blood vessels form. bpc-157 is studied for healing connective tissue — tendon, ligament, gut lining — and for bringing fresh blood supply (angiogenesis) to the repair.

Run together, TB-500 sets up the repair environment (cells arrive, vessels form) and BPC-157 rebuilds the structure in it. Because they pull different levers, the combination is additive rather than redundant — which is the whole point of a stack.

Community / practitioner convention assembled from each peptide's cited evidence — not a trial-proven combined regimen. The doses match each peptide's own page; the combination itself has not been studied head-to-head, and both peptides' strongest evidence is preclinical.

The regimen

BPC-157

Repair
Dose
250–500 mcg
Schedule
Once daily · subcutaneous
Timing
Morning; near the injury site for localized work
Reconstitution calculator

Reconstitution calculator

Calculated for a 1 mL U-100 insulin syringe (100 units/mL).

mg
mL

Units per dose

5

Draw to this mark on a U-100 syringe

Volume per dose
0.05 mL
Doses per vial
40
Concentration
5 mg/mL

One vial lasts

Daily
40 days
Every other day
80 days
5×/week
56 days

Research use only. Not for human consumption. Outputs are reference values based on research literature — verify all measurements independently.

TB-500

Cell migration
Dose
2–2.5 mg
Schedule
Twice weekly (loading) → once weekly (maintenance) · subcutaneous
Timing
Any time of day
Reconstitution calculator

Reconstitution calculator

Calculated for a 1 mL U-100 insulin syringe (100 units/mL).

mg
mL

Units per dose

10

Draw to this mark on a U-100 syringe

Volume per dose
0.1 mL
Doses per vial
20
Concentration
5 mg/mL

One vial lasts

Daily
20 days
Every other day
40 days
5×/week
28 days

Research use only. Not for human consumption. Outputs are reference values based on research literature — verify all measurements independently.

Cycle & schedule

  1. Loading (weeks 1–6)

    BPC-157 250–500 mcg once daily, plus TB-500 2–2.5 mg twice weekly (≈ 4–5 mg/week). The front-loaded TB-500 phase saturates the tissue while BPC-157 works every day.

  2. Maintenance (weeks 7–8)

    Continue BPC-157 daily; drop TB-500 to 2–2.5 mg once weekly as the repair consolidates.

  3. Washout (4 weeks)

    Stop both for about 4 weeks and reassess recovery (pain, range of motion, or imaging) before deciding whether to repeat.

Studies behind this protocol

This protocol composes the cited evidence on each peptide's page — see the full bibliography on: BPC-157, TB-500.

Research use only · Not medical advice · Updated 2026-06-01