CJC-1295 + Ipamorelin for GH optimization
CJC-1295 tells the pituitary to release GH. Ipamorelin amplifies the same pulse through a second receptor. Together the two levers produce a larger, cleaner release than either alone.
8–12 weeks + 4–6-week washout
Why this protocol
Growth hormone is released when two signals arrive together. CJC-1295 is a GHRH analog. It mimics the body's own growth-hormone-releasing hormone. Ipamorelin works on the ghrelin receptor, a separate switch that also triggers a GH pulse and is prized for being selective, since it does not meaningfully raise cortisol or prolactin.
Pushing both switches at once produces a stronger, more natural pulse than either peptide alone. That's the textbook reason this pair is run together. Timing matters. A bedtime dose stacks with the body's own largest nightly GH release, and an empty stomach keeps insulin from blunting it.
The regimen
CJC-1295
GHRH signal- Dose
- 100 mcg (no-DAC / Mod-GRF 1-29)
- Schedule
- 1–2× daily · subcutaneous
- Timing
- Bedtime, empty stomach (≥2 h fasted)
Reconstitution calculator
Reconstitution calculator
Calculated for a 1 mL U-100 insulin syringe (100 units/mL).
Units per dose
2 units
Draw this many units on a U-100 syringe
Each unit holds 50 mcg
- Volume per dose
- 0.02 mL
- Doses per vial
- 100
- Concentration
- 5 mg/mL
One vial lasts
- Daily
- 100 days
- Every other day
- 200 days
- 5×/week
- 140 days
Research use only. Not for human consumption. Outputs are reference values based on research literature. Verify all measurements independently.
Ipamorelin
Ghrelin-receptor pulse- Dose
- 200–300 mcg
- Schedule
- 1–2× daily · subcutaneous (alongside CJC-1295)
- Timing
- Bedtime; optional fasted AM
Reconstitution calculator
Reconstitution calculator
Calculated for a 1 mL U-100 insulin syringe (100 units/mL).
Units per dose
8 units
Draw this many units on a U-100 syringe
Each unit holds 25 mcg
- Volume per dose
- 0.08 mL
- Doses per vial
- 25
- Concentration
- 2.5 mg/mL
One vial lasts
- Daily
- 25 days
- Every other day
- 50 days
- 5×/week
- 35 days
Research use only. Not for human consumption. Outputs are reference values based on research literature. Verify all measurements independently.
Cycle & schedule
- Cycle (weeks 1–8 to 12)Co-inject CJC-1295 100 mcg + Ipamorelin 200–300 mcg at bedtime on an empty stomach, daily. An optional second fasted dose (e.g. morning or pre-training) can be added for a higher-frequency approach.
- Washout (4–6 weeks)Take 4–6 weeks off between cycles so pituitary sensitivity recovers; GH and IGF-1 drift back toward baseline during the break.
Studies behind this protocol
This protocol composes the cited evidence on each peptide's page. See the full bibliography on: CJC-1295, Ipamorelin.
Research use only · Not medical advice · Updated 2026-09-24