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ProtocolsLongevityBeginnerOngoing · 2–3× per week

Glutathione — Antioxidant Cycle

glutathione is the body's master antioxidant — a 2–3×/week protocol for redox and detoxification support that the body's own stores deplete under age and stress.

Why this protocol

glutathione is the cell's primary intracellular antioxidant — the molecule that neutralizes oxidative stress and supports the liver's detoxification pathways. Its levels fall with age, illness, and sustained physical or chemical stress, which is the rationale for topping it up.

It is a maintenance mono protocol rather than a fixed cycle: most run it 2–3 times a week on an ongoing basis, scaling frequency to redox demand rather than to a start-and-stop block.

Convention drawn from the Glutathione page's cited evidence — the subcutaneous dose and weekly cadence are practitioner/community convention (clinics often deliver glutathione IV), not a trial-proven longevity regimen. No therapeutic claims.

The regimen

Glutathione

Master antioxidant
Dose
400 mg per session (200 mg for maintenance)
Schedule
2–3× per week · subcutaneous
Timing
Any time of day
Reconstitution calculator

Reconstitution calculator

Calculated for a 1 mL U-100 insulin syringe (100 units/mL).

mg
mL

Units per dose

600

Draw to this mark on a U-100 syringe

Volume per dose
6 mL
Doses per vial
1
Concentration
100 mg/mL

One vial lasts

Daily
1 days
Every other day
2 days
5×/week
1 days
  • Dose volume (6 mL) exceeds the 1 mL syringe capacity. Use a larger syringe or split the draw.
  • Large draw (600 units). Double-check the vial size and dose — a mcg/mg mix-up produces values like this.

Research use only. Not for human consumption. Outputs are reference values based on research literature — verify all measurements independently.

Cycle & schedule

  1. Maintenance (ongoing)

    Glutathione 400 mg per session, 2–3× per week (200 mg for a lighter maintenance cadence). Scale frequency to redox demand rather than running a fixed start/stop block.

Studies behind this protocol

This protocol composes the cited evidence on each peptide's page — see the full bibliography on: Glutathione.

Research use only · Not medical advice · Updated 2026-06-01