GHK-Cu for skin and collagen
GHK-Cu, the copper tripeptide, drives collagen remodeling and tissue repair. It runs as a daily subcutaneous cycle for skin quality.
8–12 weeks + 4-week washout
Why this protocol
GHK-Cu is a copper-binding tripeptide that the body produces naturally and that declines with age. It is studied for remodeling the skin's support matrix, stimulating collagen and elastin, supporting wound healing, and promoting new blood-vessel growth (angiogenesis) in repairing tissue.
Here it is run as a daily subcutaneous cycle for systemic skin and connective-tissue support. (GHK-Cu is also used topically; this protocol covers the injectable route the calculator is built for.) It is a mono protocol. A single copper peptide runs on a steady daily schedule.
The regimen
GHK-Cu
Collagen remodeling- Dose
- 1 mg (1,000 mcg)
- Schedule
- Once daily · subcutaneous
- Timing
- Any time of day
Reconstitution calculator
Reconstitution calculator
Calculated for a 1 mL U-100 insulin syringe (100 units/mL).
Units per dose
4 units
Draw this many units on a U-100 syringe
Each unit holds 250 mcg
- Volume per dose
- 0.04 mL
- Doses per vial
- 50
- Concentration
- 25 mg/mL
One vial lasts
- Daily
- 50 days
- Every other day
- 100 days
- 5×/week
- 70 days
Research use only. Not for human consumption. Outputs are reference values based on research literature. Verify all measurements independently.
Cycle & schedule
- Cycle (8–12 weeks)GHK-Cu 1 mg once daily subcutaneously for 8–12 weeks; some run shorter 4–6-week blocks.
- Washout (4 weeks)A 4-week break between cycles before reassessing skin quality and deciding whether to repeat.
Studies behind this protocol
This protocol composes the cited evidence on each peptide's page. See the full bibliography on: GHK-Cu.
Research use only · Not medical advice · Updated 2026-09-24