GHK-Cu — Skin & Collagen Cycle
ghk-cu, the copper tripeptide, drives collagen remodeling and tissue repair — a daily subcutaneous cycle for skin quality.
Why this protocol
ghk-cu is a copper-binding tripeptide that the body produces naturally and that declines with age. It is studied for remodeling the skin's support matrix — stimulating collagen and elastin, supporting wound healing, and promoting new blood-vessel growth (angiogenesis) in repairing tissue.
Here it is run as a daily subcutaneous cycle for systemic skin and connective-tissue support. (GHK-Cu is also used topically; this protocol covers the injectable route the calculator is built for.) It is a mono protocol — a single copper peptide on a steady daily schedule.
Convention drawn from the GHK-Cu page's cited evidence — the injectable dose and schedule are practitioner/community convention extrapolated from the peptide's mechanism and topical/wound-healing literature, not a trial-proven systemic regimen. No therapeutic claims.
The regimen
GHK-Cu
Collagen remodeling- Dose
- 1 mg (1,000 mcg)
- Schedule
- Once daily · subcutaneous
- Timing
- Any time of day
Reconstitution calculator
Reconstitution calculator
Calculated for a 1 mL U-100 insulin syringe (100 units/mL).
Units per dose
8
Draw to this mark on a U-100 syringe
- Volume per dose
- 0.08 mL
- Doses per vial
- 25
- Concentration
- 25 mg/mL
One vial lasts
- Daily
- 25 days
- Every other day
- 50 days
- 5×/week
- 35 days
Research use only. Not for human consumption. Outputs are reference values based on research literature — verify all measurements independently.
Cycle & schedule
Cycle (8–12 weeks)
GHK-Cu 1 mg once daily subcutaneously for 8–12 weeks; some run shorter 4–6-week blocks.
Washout (4 weeks)
A 4-week break between cycles before reassessing skin quality and deciding whether to repeat.
Studies behind this protocol
This protocol composes the cited evidence on each peptide's page — see the full bibliography on: GHK-Cu.
Research use only · Not medical advice · Updated 2026-06-01