Semax + Selank for focus and calm
Semax sharpens focus and drive. Selank takes the edge off anxiety. Run together, mornings get activation and anxious moments get calm. Two separate levers instead of one.
10–14 days + 2–4-week washout
Why this protocol
Semax and Selank are short peptides developed in Russia and often used as a pair because their effects are complementary. Semax is the activating side. It is associated with raised BDNF (a protein that supports neurons), and people run it to improve focus, drive and mental stamina. Selank is the calming side, an anxiolytic that takes the edge off without the sedation of typical anti-anxiety drugs.
Running them together aims for 'switched on but not wired.' Semax covers daytime cognitive load. Selank keeps the accompanying stress response in check. Both are commonly given intranasally, which makes this an easy needle-free entry pairing, though both also exist as subcutaneous injections.
The regimen
Semax
Focus- Dose
- 300–600 mcg/day
- Schedule
- Intranasal or subcutaneous
- Timing
- Morning / daytime (activating)
Reconstitution calculator
Reconstitution calculator
Calculated for a 1 mL U-100 insulin syringe (100 units/mL).
Units per dose
16 units
Draw this many units on a U-100 syringe
Each unit holds 50 mcg
- Volume per dose
- 0.16 mL
- Doses per vial
- 12
- Concentration
- 5 mg/mL
One vial lasts
- Daily
- 12 days
- Every other day
- 25 days
- 5×/week
- 17 days
Research use only. Not for human consumption. Outputs are reference values based on research literature. Verify all measurements independently.
Selank
Calm- Dose
- 250–500 mcg/day
- Schedule
- Intranasal or subcutaneous
- Timing
- As needed for anxiety; often midday or before stress
Reconstitution calculator
Reconstitution calculator
Calculated for a 1 mL U-100 insulin syringe (100 units/mL).
Units per dose
18 units
Draw this many units on a U-100 syringe
Each unit holds 50 mcg
- Volume per dose
- 0.18 mL
- Doses per vial
- 11
- Concentration
- 5 mg/mL
One vial lasts
- Daily
- 11 days
- Every other day
- 22 days
- 5×/week
- 15 days
Research use only. Not for human consumption. Outputs are reference values based on research literature. Verify all measurements independently.
Cycle & schedule
- Course (10–14 days)Semax 300–600 mcg/day in the morning for cognitive load; Selank 250–500 mcg/day when anxiety needs taking down. Both pages cite short course lengths. Selank in particular mirrors a registered ~10–14-day clinical course.
- Washout (2–4 weeks)Take 2–4 weeks off between courses. Neither has a long-term independent safety database, so pulsed use is the cautious default.
Studies behind this protocol
Research use only · Not medical advice · Updated 2026-09-24